Lab NEWS
From Fundamental Science to Real-World Impact:
Advancing Bio-Innovation for a Safe, Secure, and Healthy Society
Through integrated research spanning from fundamental science to practical applications,we aim to create bio-innovations that contribute to a safe, secure, and healthy society.
By integrating nanotechnology, quantum metrology, artificial intelligence, and biotechnology, we pursue single-molecule science that electrically probes individual atoms, molecules, viruses, and bacteria. In particular, we are developing fifth-generation sequencing technologies capable of directly reading the nucleotide sequences of DNA and RNA, as well as the amino-acid sequences of peptides and proteins. Using these fifth-generation sequencers, we are identifying novel cancer biomarkers and developing methods for the early diagnosis of cancer.
Until now, our research has focused primarily on the development of diagnostic technologies. Going forward, we are launching new research programs aimed at detecting trace amounts of antibodies and antigens within the human body, with the ultimate goal of creating therapeutic drugs for cancer and intractable diseases. To contribute to the safety, security, and health of people worldwide—and to increase the number of smiles, even by one—we strive to translate our research outcomes into real-world applications as rapidly as possible.
While incorporating cutting-edge technologies such as quantum computing, we conduct seamless research from basic science through application, and actively promote collaboration with industry as well as the creation of startup ventures.
SANKEN, The University Osaka
Professor Masateru TANIGUTI
MISSION
At the Taniguchi Laboratory, we are pioneering the foundations of single-molecule science by developing single-molecule analytical technologies that probe the electrical conductance, temperature, heat, and structure of individual molecules using nanodevices fabricated through advanced nanotechnology.
Furthermore, by applying these single-molecule analytical techniques, we are developing single-molecule DNA and RNA sequencers and single-molecule structural analysis methods that will enable personalized medicine. Through integrated research spanning from fundamental science to practical applications, we aim to create bio-innovations that contribute to a safe, secure, and healthy society.
RESEARCH AREA
01
Single-Nano Technology
An ultra-fine manufacturing technology that enables fabrication at scales below 10 nanometers. By working in an unimaginably small world, we develop next-generation electronic and medical devices that enrich everyday life.
02
Nanogap
A novel technology that uses specially engineered electrodes separated by just 1 nanometer to detect and identify individual biomolecules—such as DNA, RNA, peptides, and neurotransmitters—one molecule at a time.
03
Nanopore
An extremely small hole, less than a few hundred nanometers in diameter, fabricated in a silicon substrate. By combining this structure with artificial intelligence, we are developing methods to distinguish viruses and bacteria individually, one by one.
Interested in Doing Research Together?
The Taniguchi Laboratory welcomes applications from prospective master’s and doctoral students from other disciplines, universities, and industry.
Our laboratory conducts cutting-edge research at the intersection of single-molecule science and biology, tackling a wide range of topics—from fundamental molecular-level understanding to the development of applied technologies. Our members collaborate by leveraging their diverse backgrounds and expertise, stimulating one another and fostering new ideas through active exchange.
If you are interested in creating bio-innovations that contribute to a safe, secure, and healthy society, please feel free to contact us via the inquiry form. Laboratory visits are also available upon request.
